Ester derivatives of hyaluronic acid for the preparation of...

C - Chemistry – Metallurgy – 08 – B

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C08B 37/08 (2006.01) A61L 27/20 (2006.01) A61L 29/04 (2006.01) A61L 31/04 (2006.01) C08J 3/075 (2006.01) C08J 3/28 (2006.01) A61K 47/36 (2006.01)

Patent

CA 2478655

The present invention relates to hyaluronic acid ester derivatives, whose carboxylic groups are partially esterified with hydroxy groups of propiophenone derivatives, to the hydrogel materials consisting of the said hyaluronic acid ester derivatives, to their preparation process by photocuring of the hyaluronic acid ester derivatives, and their use in the biomedical, sanitary and surgical fields, and in the medical field as controlled release systems for drugs.

La présente invention concerne des dérivés esters d'acide hyaluronique, dont les groupes carboxyliques sont partiellement estérifiés avec des groupes hydroxy de dérivés propiophénone. L'invention concerne également des matériaux hydrogel constitués de ces dérivés esters d'acide hyaluronique, ainsi qu'un procédé permettant de les préparer par photopolymérisation des dérivés esters d'acide hyaluronique. L'invention concerne également l'utilisation de ces dérivés dans des applications biomédicales, sanitaires et chirurgicales, ainsi que pour des applications dans le domaine médical en tant que systèmes de libération prolongée de médicaments.

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