C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/06 (2006.01) A61K 31/7068 (2006.01) A61P 31/14 (2006.01)
Patent
CA 2632626
Compounds having the formula I wherein R1 is as herein defined are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for inhibiting hepatitis replication, and processes for making the compounds of formula I.
La présente invention concerne des composés de formule I, R1 étant tel que défini dans la présente, qui représentent des inhibiteurs de la polymérase NS5b du virus de l~hépatite C. L~invention concerne également des compositions et des procédés pour inhiber la réplication de l~hépatite, ainsi que des procédés pour fabriquer les composés de la formule I.
Chun Byoung-Kwon
Clark Jeremy
Sarma Keshab
Wang Peiyuan
F. Hoffmann-La Roche Ag
Pharmasset Inc.
Ridout & Maybee Llp
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