Esterases with lipase activity

Details Esterases with lipase activity Esterases with lipase activity

C - Chemistry, Metallurgy

12

P

C12P 7/62 (2006.01) C12N 9/18 (2006.01) C12N 9/20 (2006.01) C12P 7/02 (2006.01) C12P 7/40 (2006.01) C12P 41/00 (2006.01)

Patent

CA 2475094

The present invention relates to the use of insect esterases or lipases, or mutants thereof, as catalysts in biotransformation processes. The present invention may have application in any process involving hydrolysis, esterification, transesterification, interesterification or acylation reactions. The invention also has application in the enzymatic resolution of compounds to produce optically active compounds and has particular, but not exclusive, application to substrates having a hydrophobic moiety such as pyrethroids and fatty acid esters.

L'invention concerne l'utilisation des estérases ou lipases d'insectes, ou de leurs mutants, en tant que catalyseurs dans des processus de biotransformation. La présente invention peut avoir des applications dans n'importe quel processus nécessitant des réactions d'hydrolyse, d'estérification, de transestérification, d'interesterification ou d'acylation. L'invention a aussi une application dans la résolution enzymatique des composés pour produire des composés optiquement actifs et a une application spécifique mais non exclusive avec des substrats possédant un groupe fonctionnel hydrophobe tels que les pyrethroïdes et les esters d'acides gras.

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