C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/228, 260/242
C07D 473/30 (2006.01) C07D 473/00 (2006.01) C07H 15/04 (2006.01)
Patent
CA 1159827
ABSTRACT OF THE DISCLOSURE There are prepared compounds the formula Image where R1 is alkyl of 1 to 8 carbon atoms and R2 is the ester group of an unsubstituted monocarbocylic acid aromatic carboxylic acid, aminocarboylic acid unsubstituted dicarboxylic acid, phosphoric acid, or nitric acid or a glycoside or an acetaldehyde acetal. The compounds are immunomodulators, have antiviral activity and antitumor activity and also are enzyme inhibitors. The compounds can also be used to introduce the corresponding alcohol into biological systems, in some cases with enhanced potency.
372764
Giner-Sorolla Alfredo
Guttag Alvin
Simon Lionel N.
Goudreau Gage Dubuc
Newport Pharmaceuticals International Inc.
Sloan-Kettering Institute For Cancer Research
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