Esters of 1,1,2-triphenylalkene derivatives

Details Esters of 1,1,2-triphenylalkene derivatives Esters of 1,1,2-triphenylalkene derivatives

C - Chemistry, Metallurgy

07

C

260/468, 260/474

C07C 69/035 (2006.01) A61K 31/05 (2006.01) A61K 31/135 (2006.01) A61K 31/19 (2006.01) A61K 31/21 (2006.01) A61K 31/215 (2006.01) A61K 31/22 (2006.01) A61K 31/23 (2006.01) A61K 31/235 (2006.01) A61K 31/24 (2006.01) A61K 31/275 (2006.01) A61K 31/325 (2006.01) A61K 31/395 (2006.01) C07C 39/18 (2006.01) C07D 295/08 (2006.01)

Patent

CA 1120945

ABSTRACT The disclosure relates to 1-p-aminoalkoxy- phenyl-1-p-acyloxyphenyl-2-phenylalk-1-ene derivatives, processes for their manufacture and pharmaceutical compositions containing them. The compounds possess anti-oestrogenic activity and are useful in the treatment of anovulatory infertility and of breast tumours. Representative of the compounds disclosed is 1-(p-.beta.-dimethylaminoethoxyphenyl)-trans-1-p-acetoxy- phenyl-2-p-tolybut-1-ene.

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