Esters of 1,4-ethano-10-hydroxy-5-oxo-5h-[1] benzopyrano...

Details Esters of 1,4-ethano-10-hydroxy-5-oxo-5h-[1] benzopyrano... Esters of 1,4-ethano-10-hydroxy-5-oxo-5h-[1] benzopyrano...

C - Chemistry, Metallurgy

07

D

260/272, 260/246

C07D 491/18 (2006.01)

Patent

CA 1095519

Abstract of the Disclosure Disclosed are compounds of the formula Image useful in reducing the intra-ocular pressure in mammalian patients wherein R is a straight or branched chain alkanoyl group having from 2-8 carbon atoms or Image with Y being a straight or branched chain alkylene group having from 1-8 carbon atoms; a is an integer from 1-4; b is an integer from 1-4; X is CH2, O, S, or NR1 with R1 being hydrogen or lower alkyl with the limitation that when X is O, S, or NR1, the sum of a and b is 3 or 4, and pharmaceutically acceptable acid addition salts thereof.

297028

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