Esters of 4-(1-hydroxy)-2¬acylamino)alkylamino| ethyl)phenols

C - Chemistry – Metallurgy – 07 – D

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C07D 307/68 (2006.01) C07D 213/56 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01) C07D 307/85 (2006.01) C07D 333/24 (2006.01) C07D 333/38 (2006.01) C07D 333/70 (2006.01)

Patent

CA 1189510

A B S T R A C T The invention concerns novel esters of 4-(1- hydroxy-2-[(acylamino)alkylamino]ethyl)phenols of the formula:- Image I and salts thereof, wherein R1 and R2 are (3-5C)alkyl, R3 and R4 are hydrogen or methyl, A is a direct bond or methylene, and Q is various heteroaromatic containing groups. The esters possess topical anti-inflammatory properties and the invention provides pharmaceutical compositions containing the esters and processes for their chemical manufacture.

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