Esters of acyl carnitines with long-chain aliphatic alcohols...

C - Chemistry – Metallurgy – 07 – C

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C07C 229/22 (2006.01) A61K 31/22 (2006.01)

Patent

CA 2087085

Esters of acyl L-carnitines of general formula (I) Image wherein R is a straight or branched aryl group having 2 to 16 carbon atoms, in particular isobutyryl and isovaleryl; n is an integer comprised between 7 and 15, particularly 10; and, X- is the anion of a pharmacologically acceptable acid are endowed with potent antibacterial activity. Pharmaceutical compositions comprising an ester of formula (I) can be utilized in human therapy and in the veterinary field.

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