Esters of alkoxy-acylderivatives of carnitine, process for...

C - Chemistry – Metallurgy – 07 – C

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260/487.6

C07C 229/22 (2006.01) A61K 31/14 (2006.01) A61K 31/195 (2006.01) A61K 31/205 (2006.01) A61K 31/22 (2006.01) A61K 31/24 (2006.01)

Patent

CA 1152098

"ESTERS OF ALKOXY-ACYLDERIVATIVES OF CARNITINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME" ABSTRACT OF THE DISCLOSURES A novel class of esters of alkoxy-acylderivatives of carnitine, wherein the alkoxy-acyl radical has from 3 to 6 carbon atoms (tipically: methoxyacetyl, methoxypropionyl, ethoxyacetyl, ethoxypropionyl and propoxyacetyl) is prepared by esterifying carnitine and then acylating the carnitine ester. Such esters are therapeutically useful in the treatment of cardiac disorders, hyperlipidaemias and hyperlipoproteinaemias.

378711

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