Esters of arylpropionic acids endowed with an anti-...

Details Esters of arylpropionic acids endowed with an anti-... Esters of arylpropionic acids endowed with an anti-...

C - Chemistry, Metallurgy

07

C

260/321, 260/472

C07C 69/612 (2006.01) C07D 209/46 (2006.01) C07D 333/24 (2006.01)

Patent

CA 1148166

ESTERS OF ARYLPROPIONIC ACIDS ENDOWED WITH AN ANTI-INFLAMMATORY ACTIVITY, PROCESS FOR THEIR PREPARATION, AND RELATED PHARMACEUTICAL COMPOSITIONS. ABSTRACT OF THE DISCLOSURE The present invention concerns diesters of polyethylene glycols (with n ranging between 4 approximately and 100 approximately) with 2-arylpropionic acids (known as anti- inflammatory agents). Said esters, while possessing all the characteristics of low toxicity and gastric injuring effects shown by the related acids, differ advantageously from the latter because their anti-inflammatory activity is much more prolonged, and their bioavailability markedly better.

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