C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 229/22 (2006.01) A61K 8/14 (2006.01) A61K 9/127 (2006.01)
Patent
CA 2370143
Esters of L-carnitine and alkanoyl L-carnitines are described which can be used as cationic lipids for the intracellular delivery of pharmacologically active compounds. New esters of L-carnitine and alkanoyl L-carnitines of formula (I) are also disclosed wherein the R groups are as defined in the description.
L'invention concerne des esters de L-carnitine et de L-carnitines alcanoyles, ces esters pouvant être utilisés comme lipides cationiques pour un apport intracellulaire de composés actifs d'un point de vue pharmacologique. Cette invention concerne également de nouveaux esters de L-carnitine et de L-carnitines alcanoyles de formule (I), dans laquelle les groupes R sont tels que définis dans la description.
Critelli Luciana
Pisano Claudio
Salvatori Giovanni
Santaniello Mose
Tinti Maria Ornella
Fetherstonhaugh & Co.
Sigma-Tau Industrie Farmaceutiche Riunite S.p.a.
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