C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
260/487.2
C07C 323/52 (2006.01) A61K 31/095 (2006.01) A61K 31/195 (2006.01) A61K 31/205 (2006.01) A61K 31/22 (2006.01) A61K 31/23 (2006.01) A61K 31/24 (2006.01) A61K 31/255 (2006.01) C07C 319/00 (2006.01)
Patent
CA 1167864
"Esters of mercapto acyl-carnitines, process for their prepara- tion and pharmaceutical compositions containing same". Abstract of the disclosures A novel class of esters of mercapto acyl-carnitines is dis- closed, wherein the mercapto acyl radical is the radical of sat- urated mercapto acids having from 2 to 10 carbon atoms. These esters of mercapto acyl-carnitines are prepared e.g. by first preparing the corresponding ester of halogen acyl-carnitine and then substituting therein, by nucleophylic substitution, the -SH group for the halogen atom. These esters of mercapto acyl-carnitines are useful therapeu- tic agents, e.g. for the treatment of intoxications and burns, and as mucolytic agents.
398990
Bagolini Carlo A.
de Witt Paolo
Quaresima Emma T.
Tinti Maria O.
Gowling Lafleur Henderson Llp
Sigma-Tau Industrie Farmaceutiche Riunite S.p.a
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