Esters of retinoic acid and pentaerythritol and monobenzal...

Details Esters of retinoic acid and pentaerythritol and monobenzal... Esters of retinoic acid and pentaerythritol and monobenzal...

C - Chemistry, Metallurgy

07

D

167/144, 260/352

C07D 319/06 (2006.01) A61K 31/335 (2006.01) C07C 175/00 (1985.01)

Patent

CA 1247114

ESTERS OF RETINOIC ACID AND PENTAERYTHRITOL AND MONOBENZAL ACETALS THEREOF Abstract Pentaerythritol retinoates and monobenzal acetals thereof such as (E)-2.alpha.-phenyl-5a-hydroxy- methyl-5.beta.-retinoyloxymethyl-1,3-dioxane, (E)-2.alpha.- phenyl-5.beta.-hydroxymethyl-5.alpha.-retinoyloxymethyl-1,3- dioxane, and pentaerythritol monoretinoate are dis- closed. These retinoids are useful as chemopreventive agents and as therapeutic agents for treating non- malignant skin disorders.

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