C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 1/00 (2006.01) A61K 31/565 (2006.01) A61K 31/58 (2006.01) C07J 17/00 (2006.01) C07J 21/00 (2006.01) C07J 31/00 (2006.01)
Patent
CA 2286457
This invention provides estra-5(10),7-dien-3.beta.-ol-17-one or a pharmaceutically acceptable salt of its 3-sulfate ester, estra-5(10),7-dien- 3.beta.-ol-17-one 3-glucuronide or a pharmaceutically acceptable salt thereof, estra-5(10),7-dien-3.alpha.-ol-17-one or a pharmaceutically acceptable salt of its 3-sulfate ester, estra-5(10),7-dien-3.beta.-ol-17-one 3-glucuronide or a pharmaceutically acceptable salt thereof, estra-5(10),7-dien-3.beta.-ol-17-one 3-alkali metal salt, and estra-5(10),7-dien-3.alpha.-ol-17-one 3-alkali metal salt which are useful as estrogenic agents.
L'invention décrit l'oestra-5(10),7-dièn-3.beta.-ol-17 ou un sel pharmaceutiquement acceptable de son 3-sulfate ester, l'oestra-5(10),7-dièn-3.beta.-ol-17-one 3-glucuronide ou un sel pharmaceutiquement acceptable de ce dernier, l'oestra-5(10),7-dièn-3.alpha.-ol-17-one ou un sel pharmaceutiquement acceptable de son 3-sulfate ester, l'oestra-5(10),7-dièn-3.beta.-ol-17-one 3-glucuronide ou un sel pharmaceutiquement acceptable de ce dernier, le sel de métal alcalin-3 d'oestra-5(10),7-dièn-3.beta.-ol-17-one, et le sel de métal alcalin-3 d'oestra-5(10),7-dièn-3.alpha.-ol-17-one qui sont utiles comme agents oestrogéniques.
Collins Mark Andrew
Kagan Michael Z.
Kong Fangming
Mcdonald Leonard Alexander
Raveendranath Panolil
American Home Products Corporation
Torys Llp
Wyeth
LandOfFree
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