Estradiol derivative-alkylating agent conjugate with reduced...

Details Estradiol derivative-alkylating agent conjugate with reduced... Estradiol derivative-alkylating agent conjugate with reduced...

C - Chemistry, Metallurgy

07

J

C07J 41/00 (2006.01) A61K 31/565 (2006.01) C07J 1/00 (2006.01)

Patent

CA 2133281

-32- ABSTRACT OF THE DISCLOSURE Disclosed is an estradiol derivative-alkylating agent conjugate of the formula (I'): Image (I') wherein R1 is C1-4 alkyl or C1-4 alkoxy; R2 is acyl or benzyl; m is an integer of 1 to 3; and n is an integer of 0 to 3, as a growth inhibiting agent.

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