Estradiol penetration enhancers

Details Estradiol penetration enhancers Estradiol penetration enhancers

A - Human Necessities

61

K

A61K 31/565 (2006.01) A61K 9/70 (2006.01) A61K 31/56 (2006.01) A61K 31/57 (2006.01) A61K 47/12 (2006.01) A61K 47/18 (2006.01) A61K 47/22 (2006.01)

Patent

CA 2181072

An active substance-containing patch for the controlled release of estradiol or its pharmaceutically acceptable derivatives alone or in combination with gestagens from a backing layer, an active substance-containing reservoir connected thereto and produced by using pressure sensitive adhesives and at least one penetration enhancer, and a removable protective layer is characterized by the fact that the penetration enhancer is selected from substances based on carboxylic acids.

Un pansement contenant un principe actif, permettant la distribution contrôlée d'estradiol ou de ses dérivés pharmaceutiquement admissibles, seul ou en combinaison avec des progestatifs provenant d'une couche dorsale, un réservoir associé contenant un principe actif et fabriqué au moyen d'adhésifs et au moins d'un amplificateur de pénétration, et une couche protectrice amovible, est caractérisé par le fait que l'amplificateur de pénétration est choisi parmi des substances à base d'acides carboxyliques.

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