Estrogen receptor modulators

Details Estrogen receptor modulators Estrogen receptor modulators

A - Human Necessities

61

K

A61K 31/395 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61K 31/55 (2006.01) A61P 5/00 (2006.01) C07D 205/00 (2006.01) C07D 213/02 (2006.01) C07D 327/06 (2006.01) C07D 339/08 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 411/00 (2006.01) C07D 411/04 (2006.01)

Patent

CA 2424729

The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a variety of conditions related to estrogen functioning including: bone loss, bone fractures, osteoporosis, cartilage degeneration, endometriosis, uterine fibroid disease, hot flashes, increased levels of LDL cholesterol, cardiovascular disease, impairment of cognitive functioning, cerebral degenerative disorders, restinosis, gynacomastia, vascular smooth muscle cell proliferation, obesity, incontinence, and cancer, in particular of the breast, uterus and prostate.

L'invention concerne des composés et des dérivés associés, leur synthèse et leur utilisation comme modulateurs de récepteurs d'oestrogènes. Lesdits composés sont des ligands pour les récepteurs d'oestrogènes et, comme tel, peuvent être utiles dans le traitement ou la prévention de divers états se rapportant au fonctionnement des oestrogènes, notamment: perte osseuse, fractures d'os, ostéoporose, dégénérescence des cartilages, fibrome utérin, bouffées de chaleur, taux de cholestérol LDL élevé, maladie cardio-vasculaire, déficience du fonctionnement cognitif, maladies dégénératives du cerveau, rétinose, gynécomastie, prolifération cellulaire de muscle lisse vasculaire, obésité, incontinence, et cancer, en particulier du sein, de l'utérus et de la prostate.

Affiliated with

Also associated with

Rating

Estrogen receptor modulators does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Estrogen receptor modulators, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Estrogen receptor modulators will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1467020