Estrogen receptor modulators and uses thereof

Details Estrogen receptor modulators and uses thereof Estrogen receptor modulators and uses thereof

A - Human Necessities

61

K

A61K 38/00 (2006.01) C07K 2/00 (2006.01) C07K 4/00 (2006.01) C07K 5/00 (2006.01) C07K 7/00 (2006.01) C07K 14/00 (2006.01) C07K 16/00 (2006.01) C07K 17/00 (2006.01)

Patent

CA 2536946

The present disclosure relates to the field of cellular tumorigenesis and cancer biology. More specifically, the present disclosure relates to tumorigenesis and cancer in estrogen-responsive cell types, including cell types such as testis, ovary and uterine tissues, mammary gland, brain, skeletal muscle, and lung tissues. The present disclosure further relates to compositions including polypeptides, oligopeptides, petidomimetics, antibodies, and nucleic acids, and pharmaceutical compositions, diagnostic kits, and therapeutic kits useful in the diagnosis or treatment of turnorigenesis in estrogen-responsive cell types.

L'invention a trait au domaine de la biologie du cancer et de la tumorigenèse des cellules. L'invention concerne en particulier la tumorigenèse et le cancer dans des types de cellules répondant aux oestrogènes, notamment des types de cellules des testicules, des tissus ovariens et utérins, des glandes mammaires, du cerveau, des muscles squelettiques et des tissus pulmonaires. L'invention concerne en outre des compositions contenant des polypeptides, des oligopeptides, des peptidomimétiques, des anticorps et des acides nucléiques, ainsi que des compositions pharmaceutiques et des nécessaires diagnostiques et thérapeutiques utiles pour le diagnostic ou le traitement d'une tumorigenèse dans des types de cellules répondant aux oestrogènes.

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