Ethane-1,2-diamino-bis[2r)-2-bromo-3-phenylpropanoate],...

Details Ethane-1,2-diamino-bis[2r)-2-bromo-3-phenylpropanoate],... Ethane-1,2-diamino-bis[2r)-2-bromo-3-phenylpropanoate],...

C - Chemistry, Metallurgy

07

D

C07D 513/04 (2006.01) A61K 31/55 (2006.01) A61P 9/10 (2006.01) C07C 211/63 (2006.01) C07C 219/10 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 498/04 (2006.01)

Patent

CA 2479620

The invention relates to ethane-1,2-diamino-bis[(2R)-2-bromo-3- phenylpropanoate], the production of ethane-1,2-diamino-bis[(2R)-2-bromo-3- phenylpropanoate] from (2R)-2-bromo-3-phenylpropionic acid and ethylendiamine in 2-propanol and the use of ethane-1,2-diamino-bis[(2R)-2-bromo-3- phenylpropanoate] for the production of ACE/NEP inhibitors.

L'invention concerne un éthan-1,2-diaminium-bis[(2R)-2-brome-3-phénylpropionate], la production d'un éthan-1,2-diaminium-bis[(2R)-2-brome-3-phénylpropionate] à partir d'un acide (2R)-2-brome-3-phénylpropionique et d'un diamine d'éthylène dans 2-propanol, et l'utilisation d'un éthan-1,2-diaminium-bis[(2R)-2-brome-3-phénylpropionate] destiné à la production d'inhibiteurs de ACE/NEP.

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