Ethanol-resistant sustained release formulations

Details Ethanol-resistant sustained release formulations Ethanol-resistant sustained release formulations

A - Human Necessities

61

K

A61K 9/20 (2006.01)

Patent

CA 2644992

The invention provides formulations that resist dose dumping in the presence of ethanol and methods of use thereof. The formulations can be used to prevent dose dumping, to increase safety of drugs, and to reduce abuse of drugs prone to such abuse. The formulations comprise at least one drug and a sustained release delivery system. In one embodiment, the drug is an opioid.

La présente invention concerne des formulations qui résistent à une libération massive en présence d'éthanol et des procédés d'utilisation de ces dernières. Les formulations peuvent être utilisées pour empêcher la libération massive, pour accroître l'innocuité des médicaments et pour réduire la surconsommation des médicaments pouvant engendrer une telle surconsommation. Les formulations renferment au moins un médicament et un système d'apport à libération soutenue. Dans un mode de réalisation le médicament est un opioïde.

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