C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 217/74 (2006.01) A61K 31/135 (2006.01) A61K 31/165 (2006.01) A61K 31/195 (2006.01) A61K 31/215 (2006.01) A61K 31/33 (2006.01) C07C 215/08 (2006.01) C07C 215/14 (2006.01) C07C 215/64 (2006.01) C07C 229/16 (2006.01) C07C 235/20 (2006.01) C07C 323/25 (2006.01) C07D 213/61 (2006.01) C07D 239/30 (2006.01) C07D 271/12 (2006.01) C07D 317/58 (2006.01) C07D 317/60 (2006.01)
Patent
CA 2107566
2107566 9315041 PCTABS00024 This invention relates to new ethanolamine derivatives having gut selective sympathomimetic and anti-pollakiuria activities and represented by general formula (I) wherein R1 is aryl or a heterocyclic group, each of which may be substituted with halogen, etc., R2 is hydrogen, halogen, nitro, hydroxy, lower alkyl optionally substituted with acyl, lower alkenyl optionally substituted with acyl, lower alkoxy optionally substituted with acyl, or amino optionally substituted with acyl(lower)alkyl, R3 is hydrogen, an N-protective group, or lower alkyl optionally substituted with lower alkylthio, n is an integer of 0 to 3, and a heavy solid line means a single bond or a double bond, provided that when n is 1, then 1) R1 is a condensed aromatic hydrocarbon group or a heterocyclic group, each of which may be substituted with halogen, etc., and the like, and pharmaceutically acceptable salts thereof to processes for the preparation thereof and to a pharmaceutical composition comprising the same.
Kato Takeshi
Nagano Masanobu
Shiokawa Youichi
Take Kazuhiko
Taniguchi Kiyoshi
Fujisawa Pharmaceutical Co. Ltd.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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