Ethanolate of azithromycin, process for manufacture, and...

Details Ethanolate of azithromycin, process for manufacture, and... Ethanolate of azithromycin, process for manufacture, and...

C - Chemistry, Metallurgy

07

H

C07H 17/00 (2006.01) A61K 31/7052 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2352562

A novel, non-hygroscopic form of azithromycin is disclosed, as well as a method for preparing it by the gradual crystallization of azithromycin from ethanol by the addition of a minimal amount of water to effect crystal formation. Pharmaceutical compositions containing this novel form of azithromycin are also disclosed.

La présente invention concerne une nouvelle forme d'azithromycine non hygroscopique, et son procédé de fabrication consistant à effectuer une cristallisation graduelle d'azithromycine à partir d'éthanol en ajoutant une quantité minimale d'eau de manière à former des cristaux. La présente invention concerne également des compositions pharmaceutiques contenant cette nouvelle forme d'azithromycine.

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