Ether substituted imidazopyridines

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 471/14 (2006.01) A61K 31/435 (2006.01) A61K 31/437 (2006.01) A61K 31/444 (2006.01) A61K 31/506 (2006.01) A61K 31/5377 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2488801

Imidazopyridine compounds that contain an ether functionality at the 1- position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.

Des composés d'imidazopyridine contenant une fonctionnalité éther au niveau de la position 1 sont utiles en tant que modificateurs de réponse immune. Les composés et les compositions de l'invention peuvent induire la biosynthèse de diverses cytokines et sont utiles dans le traitement de divers états notamment de maladies virales et de maladies néoplasiques. L'invention concerne également des procédés de préparation des composés ainsi que des intermédiaires utiles dans la préparation desdits composés.

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