Etheric derivative of 4/3h/-quinazolinone and a process for...

Details Etheric derivative of 4/3h/-quinazolinone and a process for... Etheric derivative of 4/3h/-quinazolinone and a process for...

C - Chemistry, Metallurgy

07

D

167/218, 260/254

C07D 239/88 (2006.01) A61K 31/505 (2006.01) C07C 39/367 (2006.01) C07C 43/225 (2006.01) C07D 239/90 (2006.01)

Patent

CA 1316924

ABSTRACT OF THE DISCLOSURE: An etheric derivative of 4(3H)-quinazolinone namely a fluorinated 3-[2-(4-biphenylyloxy)ethyl]-4(3H)-quinazoli- none, is produced by reacting said 4(3H)-quinazolinone with the corresponding fluorinated 4-(2-chloroethoxy)biphenyl. The resulting compound and its acid addition salts, especially the hydrochloride, possess substantially higher analgesic activity and lower acute toxicity than aminophena- zone, ibuprofen, acetylosalicylic acid and paracetamol.

609601

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