Ethers of 1-(2-propynyloxy) 2-amino-3-propanol

C - Chemistry – Metallurgy – 07 – D

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260/603, 260/605

C07D 295/10 (2006.01) C07D 295/088 (2006.01) C07D 295/092 (2006.01)

Patent

CA 1142926

ABSTRACT The invention is dealing with compounds of the formula: Image I and pharmaceutically acceptable salts thereof, in which R1 and R2 each represent a lower alkyl radical or a phenyl radical, or, together with the carbon atom to which they are bound, a cycloalkyl radical having at the most 7 carbon atoms; R3 represents hydrogen, a lower alkyl radical, or the phenyl radical; R4 and R5 each represent a lower alkyl radical, or, together with the nitrogen atom to which they are bound, a heterocycle amino radical such as the pyrrolidinyl or morpholino radicals; and R6 represents a lower alkyl radical, a phenyl radical, a benzyl radical, or the 1-ethynyl-cyclohexyl radical, which compounds can be used in the treatment of angina pectoris.

367499

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