Ethers of substituted hydroxymethylpyrazines

Details Ethers of substituted hydroxymethylpyrazines Ethers of substituted hydroxymethylpyrazines

C - Chemistry, Metallurgy

07

D

260/268

C07D 241/12 (2006.01)

Patent

CA 1180711

Abstract of the Disclosure The invention relates to substituted hydroxymethylpyrazine compounds of formula 1 Image (I) wherein each of the groups R, R1 and R2, which may be the same or different, represents a hydrogen atom, a C1-C6 straight or branched chain alkoxy or C1-C6 straight or branched chain alkyl group, and R3 represents a straight or branch- ed chain, saturated or unsaturated, C1-C8 aliphatic hydrocarbon group. The compounds of the invention possess an elevated lipid-lowering activity, in particular an anti-lipolytic activity (decrease of plasma free fatty acids), triglyceride-, cholesterol- and plasma phospholipid-lowering activity.

391833

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