Ethylamido fluorenes and improved method of making same

Details Ethylamido fluorenes and improved method of making same Ethylamido fluorenes and improved method of making same

C - Chemistry, Metallurgy

07

C

C07C 233/17 (2006.01) A61K 31/16 (2006.01) C07C 233/60 (2006.01) C07C 235/08 (2006.01)

Patent

CA 2178361

Novel substituted fluorene compunds of Formula I are active as melatonergic agents: Image (I) wherein: X= H, halogen, OH or OZ; Z= C1-6 alkyl;-(CH7)m-CF3 (m=0-2); CD3; or Image (m'=1-3); n=1 or 2; and R= C1-6 alkyl, C3-6 cycloalkyl, C2-4 alkenyl, halogen substituted C1-6 alkyl, or C1-6 alkoxy substituted C1-6 alkyl.

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