Ethylene diamine and guanidine derivatives

C - Chemistry – Metallurgy – 07 – D

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260/367.3, 260/2

C07D 307/34 (2006.01) C07D 307/52 (2006.01) C07D 333/20 (2006.01)

Patent

CA 1257867

ABSTRACT OF THE DISCLOSURE This invention provides compounds corresponding to the general formula: Image I wherein R1 represents a C6-C10 tricycloalkyl group, R2 represents hydrogen or a C1-C6 alkyl group, and R3 represents hydrogen, a C1-C8 alkyl group, a C3-C6-cycloalkyl group, a C3-C6-alkenyl group, a C3-C6 alkinyl group or a C1-C4 alkoxy C1-C6 alkyl group and pharmaceutically acceptable salts there- of. The compounds inhibit the secretion of gastric juice. Moreover, they have an ulcer-inhibiting and stomach-spasmoly- tic effect.

442695

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