Ethylenediamine derivatives

Details Ethylenediamine derivatives Ethylenediamine derivatives

C - Chemistry, Metallurgy

07

D

C07D 209/12 (2006.01) A61K 31/404 (2006.01) A61K 31/428 (2006.01) A61K 31/429 (2006.01) A61K 31/4365 (2006.01) A61K 31/437 (2006.01) A61K 31/4439 (2006.01) A61K 31/454 (2006.01) A61K 31/4545 (2006.01) A61K 31/4725 (2006.01) A61K 31/5025 (2006.01) A61K 31/5377 (2006.01) A61P 7/02 (2006.01) A61P 9/10 (2006.01) C07D 209/42 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 409/12 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 495/04 (2006.01) C07D

Patent

CA 2405144

Compounds of the general formula (1): Q1-Q2-C(=O)-N(R1)-Q3-N(R2)-T1-Q4; and drugs which contain the compounds and are efficacious for thrombosis and embolism. In said formula, wherein R1 and R2 are each H or the like; Q1 is an aromatic ring, a heterocycle, or the like; Q2 is a single bond, an aromatic ring, a heterocycle, or the like; Q3 is a group of the general formula (2), or the like; Q4 is an aromatic ring, a heterocycle, or the like; and T1 is -CO- or -SO2-.

L'invention concerne des composés représentés par la formule (1) Q?1¿-Q?2¿-c(=O)-N(R?1¿)-Q?3¿-N(R?2¿)-T?1¿-Q?4¿ et des médicaments contenant lesdits composés, ces composés étant efficaces pour traiter les thromboses et les embolies. Dans la formule (1), R1 et R2 représentent chacun H ou analogue; Q1 représente un cycle aromatique, un hétérocycle, ou analogue; Q2 représente une liaison simple, un cycle aromatique, un hétérocycle, ou analogue; Q3 représente un groupe représenté par la formule (2), ou analogue; Q4 représente un cycle aromatique, un hétérocycle, ou analogue; et T1 représente -CO- ou -SO2-.

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