Ethylenedicysteine (ec)-drug conjugates, compositions and...

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 47/48 (2006.01) A61K 51/04 (2006.01) C07B 59/00 (2006.01) G01T 1/161 (2006.01)

Patent

CA 2505537

The invention provides, in a general sense, a new labeling strategy employing compounds that are are N2S2 chelates conjugated to a targeting ligand, wherein the targeting ligand is a disease cell cycle targeting compound, a tumor angiogenesis targeting ligand, a tumor apoptosis targeting ligand, a disease receptor targeting ligand, amifostine, angiostatin, monoclonal antibody C225, monoclonal antibody CD31, monoclonal antibody CD40, capecitabine, COX-2, deoxycytidine, fullerene, herceptin, human serum albumin, lactose, leuteinizing hormone, pyridoxal, quinazoline, thalidomide, transferrin, or trimethyl lysine. The present invention also pertains to kits employing the compounds of interest, and methods of assessing the pharmacology of an agent of interest using the present compounds.

L'invention concerne, de façon générale, une nouvelle stratégie de marquage à l'aide de composés constitués de N¿2?S¿2?-chélates conjugués à un ligand de ciblage, ce ligand de ciblage pouvant être un composé de ciblage de cycles cellulaires de maladies, un ligand de ciblage de l'angiogenèse tumorale, un ligand de ciblage de l'apoptose tumorale, un ligand de ciblage de récepteurs associés à des maladies, l'amifostine, l'angiostatine, l'anticorps monoclonal C225, l'anticorps monoclonal CD31, l'anticorps monoclonal CD40, la capécitabine, la COX-2, la désoxycytidine, le fullerène, l'herceptine, l'albumine sérique humaine, le lactose, l'hormone lutéinisante, le pyridoxal, la quinazoline, la thalidomide, la transferrine ou la triméthyl-lysine. Ladite invention concerne également des trousses utilisant les composés d'intérêt ainsi que des méthodes d'évaluation des propriétés pharmacologiques d'un agent d'intérêt à l'aide des présents composés.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Ethylenedicysteine (ec)-drug conjugates, compositions and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Ethylenedicysteine (ec)-drug conjugates, compositions and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ethylenedicysteine (ec)-drug conjugates, compositions and... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1511060

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.