Ethynyl derivatives serving as factor xa inhibitors

Details Ethynyl derivatives serving as factor xa inhibitors Ethynyl derivatives serving as factor xa inhibitors

C - Chemistry, Metallurgy

07

D

C07D 265/32 (2006.01) A61K 31/4168 (2006.01) A61K 31/5375 (2006.01) A61K 31/5377 (2006.01) C07D 233/46 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2517391

The invention relates to novel compounds of formula (I), wherein R1, R2, R3, X and Y have the meanings as cited in Patent Claim 1. The compounds are inhibitors of coagulation factor Xa and can be used for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumors.

L'invention concerne de nouveaux composés représentés par la formule (I) dans laquelle R?1¿, R?2¿, R?3¿, X et Y ont la signification donnée dans la revendication (1). Ces composés sont des inhibiteurs du facteur de coagulation Xa et peuvent servir à la prophylaxie et/ou à la thérapie de maladies thrombo-emboliques et au traitement de tumeurs.

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