Eukaryotic expression vectors with regulation of rna processing

Details Eukaryotic expression vectors with regulation of rna processing Eukaryotic expression vectors with regulation of rna processing

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) A61K 31/70 (2006.01) A61K 35/28 (2006.01) A61K 48/00 (2006.01) C12N 5/10 (2006.01) C12N 15/867 (2006.01)

Patent

CA 2109579

2109579 9221750 PCTABS00017 The present invention relates to methods of increasing the efficiency of foreign gene expression in cells. In particular, the present invention relates to the use of retroviral vector mediated gene transfer techniques and results in methods of increasing the viral titer and the amount of protein expressed. The method of the present invention and constructs used therein are suitable for use in human gene therapy, particularly for the treatment of AIDS.

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