Evolved interferon-alpha polypeptides

Details Evolved interferon-alpha polypeptides Evolved interferon-alpha polypeptides

C - Chemistry, Metallurgy

07

K

C07K 14/56 (2006.01)

Patent

CA 2607651

The present invention provides evolved interferon-alpha polypeptides, and conjugates thereof, and nucleic acids encoding the polypeptides. The invention also includes compositions comprising these polypeptides, conjugates, and nucleic acids; cells containing or expressing the polypeptides, conjugates, and nucleic acids; methods of making the polypeptides, conjugates, and nucleic acids; and methods of using the polypeptides, conjugates, and nucleic acids.

L'invention concerne des polypeptides d'interféron-alpha mis au point génétiquement, des conjugués de ceux-ci et des acides nucléiques codant pour les polypeptides. L'invention concerne aussi des compositions comprenant ces polypeptides, conjugués et acides nucléiques; des cellules contenant ou exprimant lesdits polypeptides, conjugués et acides nucléiques; des procédés de fabrication des polypeptides, conjugués et acides nucléiques; et des procédés d'utilisation de ces polypeptides, conjugués et acides nucléiques.

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