C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/0783 (2010.01) A61K 35/12 (2006.01) A61K 35/14 (2006.01) A61K 35/28 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) A61P 37/06 (2006.01)
Patent
CA 2338773
Methods for inducing T-cell non-responsiveness to donor T-cells comprised in transplantation tissues are provided. The methods involve ex vivo treatment of donor T-cells with gp39 antagonists.
L'invention concerne des procédés d'induction d'une non-réponse des lymphocytes T à des lymphocytes T donneurs compris dans des tissus de transplantation. Ces procédés consistent à traiter ex vivo les lymphocytes T donneurs à l'aide d'antagonistes de gp39.
Blazar Bruce R.
Noelle Randolph J.
Taylor Patricia A.
Vallera Daniel A.
Regents Of The University Of Minnesota
Robic
Trustees Of Dartmouth College
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