Excitatory amino acid derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 307/93 (2006.01) A61K 31/34 (2006.01) A61K 31/38 (2006.01) A61K 31/395 (2006.01) C07D 209/52 (2006.01) C07D 333/78 (2006.01) C07D 401/02 (2006.01) C07D 403/02 (2006.01) C07D 405/02 (2006.01) C07D 407/02 (2006.01) C07D 409/02 (2006.01) C07D 413/02 (2006.01) C07D 417/02 (2006.01)

Patent

CA 2237910

Compounds for formula (I) in which X represents 0, NRa, S, S0 or S02 and R is as defined in the specification; and non-toxic metabolically labile esters or amides thereof; and pharmaceutically acceptable salts thereof are useful as modulators of metabotropic glutamate receptor function.

Des composés pour la formule (I) dans laquelle X représente O, NR<a>, S, SO, ou SO2 et R a la notation définie dans la description, ainsi que leurs esters ou amides non toxiques métabolliquement labiles, et leurs sels pharmaceutiquement acceptables sont utiles en tant que modulateurs de la fonction de récepteur du glutamate métabotrope.

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