Excitatory amino acid receptor antagonists

Details Excitatory amino acid receptor antagonists Excitatory amino acid receptor antagonists

C - Chemistry, Metallurgy

07

C

C07C 229/28 (2006.01) A61K 31/195 (2006.01) A61K 31/33 (2006.01) C07C 62/12 (2006.01) C07C 62/18 (2006.01) C07C 62/22 (2006.01) C07C 62/26 (2006.01) C07C 323/58 (2006.01) C07D 209/08 (2006.01) C07D 211/34 (2006.01) C07D 233/76 (2006.01) C07D 233/78 (2006.01) C07D 263/32 (2006.01) C07D 277/30 (2006.01) C07D 307/54 (2006.01) C07D 311/80 (2006.01) C07D 311/82 (2006.01) C07D 333/24 (2006.01) C07D 333/60 (2006.01)

Patent

CA 2199508

The present invention provides compounds of formula (I) in which R is as defined in the specification, or a pharmaceutically acceptable metabolically labile ester or amide thereof, or a pharmaceutically acceptable salt thereof, which are useful as antagonists of one or more of the actions of L-glutamate at metabotropic excitatory amino acid receptors.

Cette invention concerne des composés de formule (I), dans laquelle R est tel que défini dans le descriptif, ou un ester ou amide pharmaceutiquement acceptable de ces composés qui est métaboliquement labile, ou encore un sel pharmaceutiquement acceptable de ces composés, qu'on utilise comme antagonistes d'une ou de plusieurs actions du L-glutamate au niveau des récepteurs d'acides aminés excitateurs métabotropiques.

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