Excretable reporter systems

Details Excretable reporter systems Excretable reporter systems

C - Chemistry, Metallurgy

12

N

C12N 15/85 (2006.01) A01K 67/027 (2006.01) A61K 49/00 (2006.01) C07K 14/59 (2006.01) C12N 5/10 (2006.01) C12N 9/16 (2006.01) C12N 9/18 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2540155

The present invention provides a reporter system comprising a reporter gene encoding a reporter protein that is secretable from cells in which it produced or expressed either in vitro or in vivo and excretable in a body fluid from whole animals comprising such systems. The reporter system is useful for the detection of gene activation events or biochemical changes related to, or that occur, as a result of altered metabolic or disease status or toxicological stress in toxicological screening.

L'invention concerne un système rapporteur comprenant un gène rapporteur codant pour une protéine rapporteur qui peut être sécrétée par les cellules dans lesquelles elle est produite ou exprimée, in vitro ou in vivo, et excrétée dans un fluide corporel d'animaux entiers comprenant un tel système. Le système rapporteur permet de détecter des événements d'activation génique ou des changements biochimiques liés ou consécutifs à un état métabolique modifié, à un état pathologique ou à un stress toxicologique dans l'analyse toxicologique.

Affiliated with

Also associated with

Rating

Excretable reporter systems does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Excretable reporter systems, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Excretable reporter systems will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2078258