Exhaustive analysis of viral protein interactions by...

Details Exhaustive analysis of viral protein interactions by... Exhaustive analysis of viral protein interactions by...

C - Chemistry, Metallurgy

12

N

C12N 15/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2331786

This invention relates to the detection and analysis of viral protein-protein interactions using a two-hybrid system. This invention allows the definition and use of minimal peptides involved in these protein-protein interactions. In particular, this invention relates to the use of a two-hybrid assay to screen for molecules that interact with hepatitis C virus proteins.

L'invention concerne la détection et l'analyse d'interactions de protéine-protéine virales au moyen d'un système à deux hybrides. L'invention permet de définir et d'utiliser des peptides minimaux intervenant dans ces interactions de protéine-protéine. D'une manière spécifique, l'invention concerne l'utilisation d'un dosage à deux hybrides pour cribler des molécules qui interagissent avec des protéines du virus de l'hépatite C.

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