A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 9/48 (2006.01) A61K 47/30 (2006.01)
Patent
CA 2344672
The invention relates to a device for delaying the pylorus passage of orally administered medicament forms. Said device comprises a component which expands upon contact with the gastric juice and a polymer coat which is permeable to liquids but not to gases. The device can contain an active substance whose release into the gastric juice is mainly controlled by the medicament form into which it is incorporated. Unlike conventional medicament forms with delayed pylorus passage, the release of the active substance does not so much depend on the kind and structure of the polymer coat but is mainly determined by the incorporated medicament form. The inventive device can be easily rolled or folded and can be filled into capsules.
L'invention concerne un dispositif pour retarder le passage dans le pylore de formes médicamenteuses administrées par voie orale. Ce dispositif comporte un constituant qui gonfle au contact du suc gastrique et une enveloppe polymère qui est perméable aux liquides mais étanche aux gaz. Ce dispositif peut contenir un principe actif dont la libération dans le suc gastrique est régulée principalement par la forme médicamenteuse incorporée. A la différence des formes médicamenteuses classiques à passage retardé dans le pylore, la libération du principe actif ne dépend pas essentiellement du type et de la structure de l'enveloppe polymère, mais est déterminée principalement par la forme médicamenteuse incorporée. Le dispositif décrit se roule ou se plie aisément et peut être introduit dans des gélules.
Fetherstonhaugh & Co.
Lts Lohmann Therapie-Systeme Ag
LandOfFree
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