Expandable medical device and method for treating chronic...

A - Human Necessities – 61 – L

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A61L 31/16 (2006.01) A61F 2/06 (2006.01) A61L 29/16 (2006.01) A61L 31/04 (2006.01) A61L 31/10 (2006.01) A61F 2/00 (2006.01)

Patent

CA 2505576

A method for treating blood vessel occlusions in the heart delivers an angiogenic agent from an implantable device locally to the walls of the blood vessel over an extended administration period sufficient to establish self sustaining blood vessels. An expandable medical device for delivery of angiogenic agents includes openings in the expandable medical device struts to deliver one or more angiogenic agents to promote angiogenesis. The device can sequentially deliver a plurality of agents to promote angiogenesis to treat, for example, disorders and conditions associated with chronic total occlusions.

La présente invention se rapporte à un procédé de traitement des occlusions des vaisseaux sanguins dans le coeur, qui consiste à délivrer un agent angiogénique à partir d'un dispositif implantable, localement sur les parois des vaisseaux sanguins pendant une période d'administration prolongée suffisante pour produire des vaisseaux sanguins autosuffisants. Un dispositif médical extensible pour l'administration d'agents angiogéniques comporte des ouvertures formées dans les contrefiches du dispositif médical extensible et conçues pour délivrer un ou plusieurs agents angiogéniques favorisant l'angiogenèse. Le dispositif peut délivrer séquentiellement une pluralité d'agents favorisant l'angiogenèse de manière à traiter, par exemple, les troubles et les états pathologiques associés à des occlusions totales chroniques.

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