Export and modification of (poly)peptides in the lantibiotic...

Details Export and modification of (poly)peptides in the lantibiotic... Export and modification of (poly)peptides in the lantibiotic...

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) C07K 14/00 (2006.01) C07K 14/315 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2487351

The invention includes a method for harvesting a polypeptide produced by a host cell, wherein the polypeptide has not undergone intra-cellular post- translational modification, such as dehydration of a serine or a threonine, and/or thioether bridge formation. The invention also includes a method for producing thioether containing peptides and dehydroalanine/dehydrobutyrine- containing peptides, wherein extracellularly thioether rings may be formed.

L'invention concerne un procédé pour récolter un polypeptide produit par une cellule hôte, ce polypeptide n'ayant pas subi de modification post-translationnelle intracellulaire, telle que la déshydratation d'une sérine ou d'une thréonine et/ou la formation d'un pont thioéther. La présente invention porte également sur un procédé pour produire des peptides contenant du thioéther et des peptides contenant de la déhydroalanine/déhydrobutyrine, des cycles thioéther extracellulaires pouvant alors se former.

Affiliated with

Also associated with

Rating

Export and modification of (poly)peptides in the lantibiotic... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Export and modification of (poly)peptides in the lantibiotic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Export and modification of (poly)peptides in the lantibiotic... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2061287