Expression analysis of smarc nucleic acids and polypeptides...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2429723

The invention relates to compositions, kits, and methods for detecting, characterizing, preventing, and treating prostate cancer. SWI/SNF-related matrix-associated actin-dependent regulator of chromatin (SMARC) markers are provided, wherein changes in the levels of expression of one or more of the SMARC markers is correlated with the presence of prostate cancer.

L'invention concerne des compositions, des trousses et des méthodes destinées à détecter, caractériser, prévenir et traiter le cancer de la prostate. Plus particulièrement, l'invention se rapporte à des marqueurs du régulateur de chromatine dépendant de l'actine, associé à la matrice et lié à SWI/SNF (SMARC). Les changements des niveaux d'expression d'un ou de plusieurs de ces marqueurs SMARC sont corrélés avec la présence d'un cancer de la prostate.

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