C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/48 (2006.01) A61K 35/76 (2006.01) A61K 39/21 (2006.01) C07H 21/00 (2006.01) C12N 5/10 (2006.01) C12N 7/01 (2006.01) C12N 15/86 (2006.01)
Patent
CA 2116253
ABSTRACT OF THE INVENTION This invention relates to the treatment of disease states, and especially AIDS, through the administration of antisense and other nucleotide constructs. The constructs are administered to the patient in a traditionally pharmaceutical manner, or through the use of recombinant retrovirus delivery systems. The latter delivery systems preferably target specific cell types or other components one desires totarget. Such targeting is accomplished by modifying the envelope of a recombinantly produced therapeutic retrovirus to contain ligand (receptor) sequences for which a receptor (ligand) exists on the cell type or other component in question.
Ortho Pharmaceutical Corporation
Swabey Ogilvy Renault
LandOfFree
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