Expression control using variable intergenic sequences

Details Expression control using variable intergenic sequences Expression control using variable intergenic sequences

C - Chemistry, Metallurgy

07

K

C07K 16/00 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01) C12N 1/21 (2006.01) C12N 15/70 (2006.01) C12N 15/72 (2006.01)

Patent

CA 2466629

The present invention relates to a method of production of antibodies wherein the heavy and light chains of a particular antibody molecule are encoded by the DNA present in a dicistronic message in which the two cistrons are linked by an optimised intergenic sequence.

L'invention concerne un procédé de production d'anticorps dans lesquels les chaînes lourdes et les chaînes légères d'une molécule d'anticorps particulière sont codées par l'ADN présent dans un message dicistronique dans lequel les deux cistrons sont liés par une séquence intergénique optimisée.

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