Expression of a foamy virus envelope protein

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/48 (2006.01) A61K 31/70 (2006.01) A61K 35/12 (2006.01) A61K 39/21 (2006.01) A61K 48/00 (2006.01) C07K 14/15 (2006.01) C07K 14/16 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12N 7/01 (2006.01) C12N 7/04 (2006.01) C12N 15/62 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2229515

The invention concerns constructs for the expression of a protein comprising at least a modified FV envelope protein, the protein so obtained as well as the complementation cell line permitting the production of pseudotyped viral particle. It also concerns pharmaceutical composition comprising said particles and a method for treating a disease.

L'invention concerne des constructions pour l'expression d'une protéine comportant au moins une protéine de coque de spumavirus modifiée, la protéine ainsi obtenue, de même que la lignée cellulaire de complémentation permettant la production de particules virales pseudotypées. L'invention a également trait à une composition pharmaceutique comprenant les particules en question et à une méthode de traitement d'une maladie.

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