Expression of a foamy virus envelope protein

Details Expression of a foamy virus envelope protein Expression of a foamy virus envelope protein

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 35/76 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12N 7/04 (2006.01)

Patent

CA 2199989

The invention concerns constructs for the expression of a protein comprising at least a modified FV envelope protein, the protein so obtained as well as the complementation cell line permitting the production of pseudotyped viral particle. It also concerns pharmaceutical composition comprising said particles and a method for treating a disease.

L'invention concerne des structures pour l'expression d'une protéine comprenant au moins une protéine d'enveloppe modifiée de virus spumeux (FV), la protéine ainsi obtenue de même que la lignée cellulaire de complémentation permettant la production de la particule virale pseudotypée. Elle a aussi trait à la composition pharmaceutique comprenant de telles particules et à une méthode pour traiter une maladie.

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