C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 9/127 (2006.01) A61K 48/00 (2006.01) C07K 14/16 (2006.01) C07K 14/61 (2006.01) C12N 9/02 (2006.01) C12N 9/10 (2006.01) C12N 9/12 (2006.01) C12N 9/78 (2006.01) C12N 15/52 (2006.01) C12N 15/87 (2006.01)
Patent
CA 2049287
A method for delivering an isolated polynucleotide to the interior of a cell in a vertebrate, comprising the interstitial introduction of an isolated polynucleotide into a tissue of the vertebrate where the polynucleotide is taken up by the cells of the tissue and exerts a therapeutic effect on the vertebrate. The method can be used to deliver a therapeutic polypeptide to the cells of the vertebrate, to provide an immune response upon in vivo translation of the polynucleotide, to deliver antisense polynucleotides, to deliver receptors to the cells of the vertebrate, or to provide transitory gene therapy.
Carson Dennis A.
Felgner Philip L.
Malone Robert W.
Rhodes Gary H.
Wolff Jon A.
Mbm Intellectual Property Law Llp
Vical Incorporated
Wisconsin Alumni Research Foundation
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