Expression of genes in modified vaccinia virus ankara by...

Details Expression of genes in modified vaccinia virus ankara by... Expression of genes in modified vaccinia virus ankara by...

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) C12N 15/861 (2006.01) C12N 15/863 (2006.01)

Patent

CA 2481783

The invention concerns recombinant Modified vaccinia virus Ankara comprising in the viral genome an expression cassette comprising the cowpox ATI promoter or a derivative thereof and a coding sequence, wherein the expression of the coding sequence is regulated by said promoter. The virus may be useful as a vaccine or as part of a pharmaceutical composition.

L'invention concerne le virus vaccinal modifié de recombinaison Ankara comprenant dans le génome viral une cassette d'expression contenant le promoteur vaccinal ATI ou un dérivé de celui-ci et une séquence de codage, l'expression de la séquence de codage étant régulée par ledit promoteur. Le virus peut être utilisé en tant que vaccin ou partie d'une composition pharmaceutique.

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