Expression of human apolipoproteins ai and ai-milano in yeast

Details Expression of human apolipoproteins ai and ai-milano in yeast Expression of human apolipoproteins ai and ai-milano in yeast

C - Chemistry, Metallurgy

12

N

C12N 15/81 (2006.01) A61K 38/17 (2006.01) C07K 14/395 (2006.01) C07K 14/775 (2006.01) C12N 1/19 (2006.01) C12N 15/12 (2006.01) C12N 15/62 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2053288

An expression vector capable of expressing, in a transformed yeast, apolipoprotein AI and mutant apolipoprotein AI-M (Milano) is described. Yeast strains, namely of S.cerevisiae, transformed by said vectors, produce the protein which may be conveniently purified and used for the treatment of atherosclerosis and cardiovascular diseases.

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