Expression of human cmv glycoprotein-h using the...

Details Expression of human cmv glycoprotein-h using the... Expression of human cmv glycoprotein-h using the...

C - Chemistry, Metallurgy

12

N

C12N 15/38 (2006.01) A61K 39/245 (2006.01) C07K 14/045 (2006.01) C12N 5/10 (2006.01) C12N 15/86 (2006.01) C12N 15/866 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2088599

2088599 9202628 PCTABS00010 Methods for producing recombinant polypeptides which are immunological equivalents of human cytomegalovirus glycoprotein H are disclosed. The methods involve the modification of native CMV gH by C-terminal truncation and subsequent expression in baculovirus/insect cell expression systems. Also disclosed are vectors, recombinant cells and modified recombinant glycoproteins.

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